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N.I.H. Says Bat Analysis Group Did not Report Findings on Time

N.I.H. Says Bat Analysis Group Did not Report Findings on Time

N.I.H. Says Bat Research Group Failed to Report Findings on Time




Public Well being Service


Nationwide Institutes of Well being Bethesda, Maryland 20892

October 20, 2021

The Honorable James Comer Rating Member, Committee on Oversight and Reform U.S. Home of Representatives Washington, D.C. 20515

Pricey Consultant Comer:

Thanks on your continued curiosity within the work of the Nationwide Institutes of Well being (NIH). I’m writing immediately to supply further info and paperwork concerning NIH’s grant to EcoHealth Alliance, Inc.

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You will need to state on the outset that revealed genomic knowledge exhibit that the bat coronaviruses studied underneath the NIH grant to EcoHealth Alliance, Inc. and subaward to the Wuhan Institute of Virology (WIV) should not and couldn’t have change into SARS-CoV-2. Each the progress report and the evaluation connected right here once more verify that conclusion, because the sequences of the viruses are genetically very distant.

The fifth and ultimate progress report for Grant RO1AI1 10964, awarded to EcoHealth Alliance, Inc. is connected with redactions just for personally identifiable info. This progress report was submitted to NIH in August 2021 in response to NIH’s compliance enforcement efforts. It consists of knowledge from a analysis venture carried out throughout the 2018-19 grant interval utilizing bat coronavirus genome sequences already present in nature.

The restricted experiment described within the ultimate progress report supplied by EcoHealth Alliance was testing if spike proteins from naturally occurring bat coronaviruses circulating in China had been able to binding to the human ACE2 receptor in a mouse mannequin. All different facets of the mice, together with the immune system, remained unchanged. On this restricted experiment, laboratory mice contaminated with the SHC014 WIV1 bat coronavirus turned sicker than these contaminated with the WIV1 bat coronavirus. As typically happens in science, this was an sudden results of the analysis, versus one thing that the researchers got down to do. Regardless, the viruses being studied underneath this grant had been genetically very distant from SARS-CoV-2.

The analysis plan was reviewed by NIH prematurely of funding, and NIH decided that it did to not match the definition of analysis involving enhanced pathogens of pandemic potential (ePPP) as a result of these bat coronaviruses had not been proven to contaminate people. As such, the analysis was not topic to departmental assessment underneath the HHS P3CO Framework. Nonetheless, out of an abundance of warning and as an extra layer of oversight, language was included within the phrases and situations of the grant award to EcoHealth that outlined standards for a secondary assessment, corresponding to a requirement that the grantee report instantly a one log improve in development. These

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